At the level of the National Health System (NHS), HTA is carried out by the Spanish Network of Agencies for Health Technology Assessment and Benefits of the NHS. Seven regional agencies are included in this Network. It is ascribed to the Directorate General of Common NHS Portfolio and Pharmacy of the Ministry of Health. In the assessment reports, considerations about the following aspects are included:  • Economic aspects: Estimated budgetary impact, costs and resources required for their implementation; e.g. efficiency of the technology, relationship between costs and health outcomes of the evaluated technology.  • Organizational aspects: organizational changes resulting from the implementation;  • Ethical, social and legal aspects, ethical, social and legal disputes arising from implementation.